Fine lines and wrinkles are a natural part of aging, but Botox, Dysport, and Xeomin offer a simple, non-surgical way to smooth them. While all three work by relaxing facial muscles to reduce wrinkles, they have distinct differences in formulation, diffusion, and results. If you are considering neurotoxin injections but are unsure which option is best, this guide will break down how they compare and which one may be right for you.
How Do Neurotoxin Injections Work?
Botox, Dysport, and Xeomin contain botulinum toxin type A, which temporarily blocks nerve signals to targeted muscles. This reduces movement in areas where wrinkles form, leading to a smoother, refreshed appearance. These treatments are commonly used for:
- Forehead lines
- Frown lines (11s between the brows)
- Crow’s feet around the eyes
- Bunny lines on the nose
- Lip lines and gummy smiles
- Jawline slimming and neck bands
While they work in a similar way, the key differences lie in how they spread, how quickly they take effect, and how they interact with the skin.
Botox, Dysport, and Xeomin: Key Differences
Botox: The Gold Standard in Wrinkle Relaxation
- Best for: Targeted wrinkle reduction, first-time patients, and smaller treatment areas
Botox is the most well-known neurotoxin and has been used for cosmetic wrinkle reduction since 2002. It is highly precise, making it a great choice for treating smaller, well-defined areas such as crow’s feet and frown lines. Botox has a slightly firmer hold, which helps maintain a controlled and natural-looking result.
- Results Appear: Five to seven days after treatment
- How Long It Lasts: Three to four months
Dysport: The Fast-Acting, Natural-Looking Option
- Best for: Larger treatment areas like the forehead and patients wanting a softer, blended look
Dysport spreads more easily than Botox, making it ideal for larger areas such as the forehead. Because of its diffusion effect, Dysport creates a softer, more natural appearance that blends seamlessly into surrounding areas. It also kicks in faster than Botox, with results visible in two to three days.
- Results Appear: Two to three days after treatment
- How Long It Lasts: Three to four months
Xeomin: The Purified Neurotoxin
- Best for: Patients who have developed resistance to Botox or prefer an additive-free formula
Xeomin is often called the “naked Botox” because it contains only botulinum toxin A, without extra proteins or additives. This makes it an ideal choice for patients who have built a resistance to Botox or Dysport over time. Because it is a pure formulation, it may also be less likely to trigger an immune response in long-term users.
- Results Appear: Four to seven days after treatment
- How Long It Lasts: Three to four months
Which Wrinkle Relaxer Is Right for You?
The best neurotoxin for you depends on your goals, facial structure, and treatment preferences.
- Choose Botox if you want precise, well-targeted wrinkle correction for smaller areas.
- Choose Dysport if you prefer a faster-acting, more diffused effect on larger areas like the forehead.
- Choose Xeomin if you need a pure formulation without additives or have developed resistance to Botox.
A consultation with a board-certified dermatologist can help determine the best option based on your facial anatomy and skincare goals.